Ontology highlight
ABSTRACT:
SUBMITTER: Grytten I
PROVIDER: S-EPMC6396939 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Grytten Ivar I Rand Knut D KD Nederbragt Alexander J AJ Storvik Geir O GO Glad Ingrid K IK Sandve Geir K GK
PLoS computational biology 20190219 2
Graph-based representations are considered to be the future for reference genomes, as they allow integrated representation of the steadily increasing data on individual variation. Currently available tools allow de novo assembly of graph-based reference genomes, alignment of new read sets to the graph representation as well as certain analyses like variant calling and haplotyping. We here present a first method for calling ChIP-Seq peaks on read data aligned to a graph-based reference genome. Th ...[more]