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Cannabis and mental illness: a review.


ABSTRACT: With the increasing push to legalize cannabis in Western nations, there is a need to gage the potential impact of this policy change on vulnerable populations, such as those with mental illness, including schizophrenia, mood, and anxiety disorders. This is particularly important as there are strong motives in these individuals to seek short-term reward (e.g., "getting high"). Nonetheless, data to support the beneficial effects of cannabis use in psychiatric populations are limited, and potential harms in patients with psychotic and mood disorders have been increasingly documented. This article reviews the effects of cannabis in people with mental illness. Then, we provide a reconciliation of the addiction vulnerability and allostatic hypotheses to explain co-morbidity addiction in mentally ill cannabis users, as well as to further aid in developing a rational framework for the assessment and treatment of problematic cannabis use in these patients.

SUBMITTER: Lowe DJE 

PROVIDER: S-EPMC6397076 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature

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Cannabis and mental illness: a review.

Lowe Darby J E DJE   Sasiadek Julia D JD   Coles Alexandria S AS   George Tony P TP  

European archives of psychiatry and clinical neuroscience 20181219 1


With the increasing push to legalize cannabis in Western nations, there is a need to gage the potential impact of this policy change on vulnerable populations, such as those with mental illness, including schizophrenia, mood, and anxiety disorders. This is particularly important as there are strong motives in these individuals to seek short-term reward (e.g., "getting high"). Nonetheless, data to support the beneficial effects of cannabis use in psychiatric populations are limited, and potential  ...[more]

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