Ontology highlight
ABSTRACT:
SUBMITTER: Savoji H
PROVIDER: S-EPMC6397087 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Savoji Houman H Mohammadi Mohammad Hossein MH Rafatian Naimeh N Toroghi Masood Khaksar MK Wang Erika Yan EY Zhao Yimu Y Korolj Anastasia A Ahadian Samad S Radisic Milica M
Biomaterials 20181001
Cardiovascular disease is the leading cause of death worldwide. Although investment in drug discovery and development has been sky-rocketing, the number of approved drugs has been declining. Cardiovascular toxicity due to therapeutic drug use claims the highest incidence and severity of adverse drug reactions in late-stage clinical development. Therefore, to address this issue, new, additional, replacement and combinatorial approaches are needed to fill the gap in effective drug discovery and sc ...[more]