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Antiviral therapy predicts the outcomes following resection of hepatocellular carcinoma in patients negative for HBV DNA: a propensity score matching analysis.


ABSTRACT: BACKGROUND:The effect of antiviral therapy (AVT) on clinical outcomes in patients with hepatocellular carcinoma (HCC) who are seronegative for hepatitis B virus (HBV), defined as HBV DNA

SUBMITTER: Xu M 

PROVIDER: S-EPMC6397498 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

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Antiviral therapy predicts the outcomes following resection of hepatocellular carcinoma in patients negative for HBV DNA: a propensity score matching analysis.

Xu Mingxing M   Zhou Zheng Z   Xu Ruiyun R   Zhang Huiling H   Lin Nan N   Zhong Yuesi Y  

World journal of surgical oncology 20190301 1


<h4>Background</h4>The effect of antiviral therapy (AVT) on clinical outcomes in patients with hepatocellular carcinoma (HCC) who are seronegative for hepatitis B virus (HBV), defined as HBV DNA < 100 IU/ml prior to surgical resection, is unknown. The main purpose of this study was to evaluate the possible value of AVT in this cohort of patients.<h4>Methods</h4>From January 2006 to January 2013, 161 HCC patients with positive serum tests for HBV surface antigen (HBsAg) but negative tests for HBV  ...[more]

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