Attitudes of Potential Participants Towards Molecular Therapy Trials in Huntington's Disease.

ABSTRACT:

Background

Advances in molecular therapeutic approaches in the last decade are translating into the design of non-traditional clinical trials. In order to improve their feasibility, it is important to understand the attitudes of potential participants towards these trials, their motivations to get involved and acceptance of risks.

Objective

We aimed to better understand the willingness of potential participants to participate in different molecular therapy trials for Huntington's disease (HD) based on their clinical and genetic status, trial design and goals of the treatment.

Methods

An anonymous survey was distributed through the Huntington's Disease Society of America (HDSA) on-line portal/website. Various hypothetical scenarios were presented followed by a survey c

SUBMITTER: Bardakjian TM 

PROVIDER: S-EPMC6398921 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature