Atypical functional connectome hierarchy in autism.
Ontology highlight
ABSTRACT:
SUBMITTER: Hong SJ
PROVIDER: S-EPMC6399265 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Publications
Atypical functional connectome hierarchy in autism.
Hong Seok-Jun SJ Vos de Wael Reinder R Bethlehem Richard A I RAI Lariviere Sara S Paquola Casey C Valk Sofie L SL Milham Michael P MP Di Martino Adriana A Margulies Daniel S DS Smallwood Jonathan J Bernhardt Boris C BC
Nature communications 20190304 1
One paradox of autism is the co-occurrence of deficits in sensory and higher-order socio-cognitive processing. Here, we examined whether these phenotypical patterns may relate to an overarching system-level imbalance-specifically a disruption in macroscale hierarchy affecting integration and segregation of unimodal and transmodal networks. Combining connectome gradient and stepwise connectivity analysis based on task-free functional magnetic resonance imaging (fMRI), we demonstrated atypical con ...[more]
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