Ontology highlight
ABSTRACT:
SUBMITTER: Liu YL
PROVIDER: S-EPMC6399327 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Liu Yen-Liang YL Chou Chao-Kai CK Kim Mirae M Vasisht Rohan R Kuo Yu-An YA Ang Phyllis P Liu Cong C Perillo Evan P EP Chen Yu-An YA Blocher Katherine K Horng Hannah H Chen Yuan-I YI Nguyen Duc Trung DT Yankeelov Thomas E TE Hung Mien-Chie MC Dunn Andrew K AK Yeh Hsin-Chih HC
Scientific reports 20190304 1
Derailed transmembrane receptor trafficking could be a hallmark of tumorigenesis and increased tumor invasiveness, but receptor dynamics have not been used to differentiate metastatic cancer cells from less invasive ones. Using single-particle tracking techniques, we developed a phenotyping asssay named Transmembrane Receptor Dynamics (TReD), studied the dynamics of epidermal growth factor receptor (EGFR) in seven breast epithelial cell lines and developed a phenotyping assay named Transmembran ...[more]