Ontology highlight
ABSTRACT:
SUBMITTER: Kannan M
PROVIDER: S-EPMC6399427 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Kannan Madhuvanthi M Vasan Ganesh G Pieribone Vincent A VA
Frontiers in cellular neuroscience 20190226
Genetically encoded optical indicators of neuronal activity enable unambiguous recordings of input-output activity patterns from identified cells in intact circuits. Among them, genetically encoded voltage indicators (GEVIs) offer additional advantages over calcium indicators as they are direct sensors of membrane potential and can adeptly report subthreshold events and hyperpolarization. Here, we outline the major GEVI designs and give an account of properties that need to be carefully optimize ...[more]