Ontology highlight
ABSTRACT:
SUBMITTER: Denton AE
PROVIDER: S-EPMC6400543 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Denton Alice E AE Innocentin Silvia S Carr Edward J EJ Bradford Barry M BM Lafouresse Fanny F Mabbott Neil A NA Mörbe Urs U Ludewig Burkhard B Groom Joanna R JR Good-Jacobson Kim L KL Linterman Michelle A MA
The Journal of experimental medicine 20190205 3
Ectopic lymphoid structures form in a wide range of inflammatory conditions, including infection, autoimmune disease, and cancer. In the context of infection, this response can be beneficial for the host: influenza A virus infection-induced pulmonary ectopic germinal centers give rise to more broadly cross-reactive antibody responses, thereby generating cross-strain protection. However, despite the ubiquity of ectopic lymphoid structures and their role in both health and disease, little is known ...[more]