Ontology highlight
ABSTRACT:
SUBMITTER: Kozuka T
PROVIDER: S-EPMC6401137 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Kozuka Takashi T Omori Yoshihiro Y Watanabe Satoshi S Tarusawa Etsuko E Yamamoto Haruka H Chaya Taro T Furuhashi Mayu M Morita Makiko M Sato Tetsuya T Hirose Shinichi S Ohkawa Yasuyuki Y Yoshimura Yumiko Y Hikida Takatoshi T Furukawa Takahisa T
Scientific reports 20190305 1
MicroRNA-124 (miR-124) is evolutionarily highly conserved among species and one of the most abundantly expressed miRNAs in the developing and mature central nervous system (CNS). Previous studies reported that miR-124 plays a role in CNS development, such as neuronal differentiation, maturation, and survival. However, the role of miR-124 in normal brain function has not yet been revealed. Here, we subjected miR-124-1<sup>+/-</sup> mice, to a comprehensive behavioral battery. We found that miR-12 ...[more]