Ontology highlight
ABSTRACT:
SUBMITTER: Nkurunungi G
PROVIDER: S-EPMC6401159 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Nkurunungi Gyaviira G van Diepen Angela A Nassuuna Jacent J Sanya Richard E RE Nampijja Margaret M Nambuya Irene I Kabagenyi Joyce J Serna Sonia S Reichardt Niels-Christian NC van Ree Ronald R Webb Emily L EL Elliott Alison M AM Yazdanbakhsh Maria M Hokke Cornelis H CH
Scientific reports 20190305 1
Core β-1,2-xylose and α-1,3-fucose are antigenic motifs on schistosome N-glycans, as well as prominent IgE targets on some plant and insect glycoproteins. To map the association of schistosome infection with responses to these motifs, we assessed plasma IgE and IgG reactivity using microarray technology among Ugandans from rural Schistosoma mansoni (Sm)-endemic islands (n = 209), and from proximate urban communities with lower Sm exposure (n = 62). IgE and IgG responses to core β-1,2-xylose and ...[more]