Dietary nitrate's effects on exercise performance in heart failure with reduced ejection fraction (HFrEF).
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ABSTRACT:
SUBMITTER: Mulkareddy V
PROVIDER: S-EPMC6401215 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
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Dietary nitrate's effects on exercise performance in heart failure with reduced ejection fraction (HFrEF).
Mulkareddy Vinaya V Racette Susan B SB Coggan Andrew R AR Peterson Linda R LR
Biochimica et biophysica acta. Molecular basis of disease 20180924 4
Heart failure with reduced ejection fraction (HFrEF) is a deadly and disabling disease. A key derangement contributing to impaired exercise performance in HFrEF is decreased nitric oxide (NO) bioavailability. Scientists recently discovered the inorganic nitrate pathway for increasing NO. This has advantages over organic nitrates and NO synthase production of NO. Small studies using beetroot juice as a source of inorganic nitrate demonstrate its power to improve exercise performance in HFrEF. A l ...[more]
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