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The comparative genomics and complex population history of Papio baboons.


ABSTRACT: Recent studies suggest that closely related species can accumulate substantial genetic and phenotypic differences despite ongoing gene flow, thus challenging traditional ideas regarding the genetics of speciation. Baboons (genus Papio) are Old World monkeys consisting of six readily distinguishable species. Baboon species hybridize in the wild, and prior data imply a complex history of differentiation and introgression. We produced a reference genome assembly for the olive baboon (Papio anubis) and whole-genome sequence data for all six extant species. We document multiple episodes of admixture and introgression during the radiation of Papio baboons, thus demonstrating their value as a model of complex evolutionary divergence, hybridization, and reticulation. These results help inform our understanding of similar cases, including modern humans, Neanderthals, Denisovans, and other ancient hominins.

SUBMITTER: Rogers J 

PROVIDER: S-EPMC6401983 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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The comparative genomics and complex population history of <i>Papio</i> baboons.

Rogers Jeffrey J   Raveendran Muthuswamy M   Harris R Alan RA   Mailund Thomas T   Leppälä Kalle K   Athanasiadis Georgios G   Schierup Mikkel Heide MH   Cheng Jade J   Munch Kasper K   Walker Jerilyn A JA   Konkel Miriam K MK   Jordan Vallmer V   Steely Cody J CJ   Beckstrom Thomas O TO   Bergey Christina C   Burrell Andrew A   Schrempf Dominik D   Noll Angela A   Kothe Maximillian M   Kopp Gisela H GH   Liu Yue Y   Murali Shwetha S   Billis Konstantinos K   Martin Fergal J FJ   Muffato Matthieu M   Cox Laura L   Else James J   Disotell Todd T   Muzny Donna M DM   Phillips-Conroy Jane J   Aken Bronwen B   Eichler Evan E EE   Marques-Bonet Tomas T   Kosiol Carolin C   Batzer Mark A MA   Hahn Matthew W MW   Tung Jenny J   Zinner Dietmar D   Roos Christian C   Jolly Clifford J CJ   Gibbs Richard A RA   Worley Kim C KC  

Science advances 20190130 1


Recent studies suggest that closely related species can accumulate substantial genetic and phenotypic differences despite ongoing gene flow, thus challenging traditional ideas regarding the genetics of speciation. Baboons (genus <i>Papio</i>) are Old World monkeys consisting of six readily distinguishable species. Baboon species hybridize in the wild, and prior data imply a complex history of differentiation and introgression. We produced a reference genome assembly for the olive baboon (<i>Papi  ...[more]

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