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Hyperbilirubinemia predicts the infectious complications after esophagectomy for esophageal cancer.


ABSTRACT: Background:Surgical stress and inflammation can cause hyperbilirubinemia, which sometimes occurs after esophagectomy for esophageal cancer (EC). The aim of this study was to elucidate the clinical significance of postoperative hyperbilirubinemia in the management of EC patients. Materials and methods:We retrospectively reviewed records of 81?EC patients who underwent esophagectomy from 2009 to 2014. We compared the clinicopathological and perioperative factors, including the presence of hyperbilirubinemia (total bilirubin ?1.5?mg/dL), between patients with postoperative infectious complications (PIC group) and those without (Non-PIC group). Results:PIC developed in 52 patients (64.2%). There were significant differences in incidence of postoperative hyperbilirubinemia between the PIC group and the non-PIC group (34.6% vs. 3.4%, P?=?0.002), as well as the approach of esophagectomy (P?=?0.045), the surgical duration (469 vs. 389 min, P?

SUBMITTER: Muneoka Y 

PROVIDER: S-EPMC6402227 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

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Hyperbilirubinemia predicts the infectious complications after esophagectomy for esophageal cancer.

Muneoka Yusuke Y   Ichikawa Hiroshi H   Kosugi Shin-Ichi SI   Hanyu Takaaki T   Ishikawa Takashi T   Kano Yosuke Y   Shimada Yoshifumi Y   Nagahashi Masayuki M   Sakata Jun J   Kobayashi Takashi T   Kameyama Hitoshi H   Akazawa Kohei K   Wakai Toshifumi T  

Annals of medicine and surgery (2012) 20190221


<h4>Background</h4>Surgical stress and inflammation can cause hyperbilirubinemia, which sometimes occurs after esophagectomy for esophageal cancer (EC). The aim of this study was to elucidate the clinical significance of postoperative hyperbilirubinemia in the management of EC patients.<h4>Materials and methods</h4>We retrospectively reviewed records of 81 EC patients who underwent esophagectomy from 2009 to 2014. We compared the clinicopathological and perioperative factors, including the prese  ...[more]

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