Ontology highlight
ABSTRACT:
SUBMITTER: Liu Y
PROVIDER: S-EPMC6402263 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Liu Yang Y Maekawa Toshio T Yoshida Keisuke K Muratani Masafumi M Chatton Bruno B Ishii Shunsuke S
iScience 20190218
Adipocytes function as major players in the regulation of metabolic homeostasis, and factors contributing to adipocyte differentiation and function are promising targets for combatting obesity and associated metabolic disorders. Activating transcription factor 7 (ATF7), a stress-responsive chromatin regulator, is involved in energy metabolism, but the underlying mechanisms remain unknown. Herein, we showed that ATF7 is required for adipocyte differentiation and interacts with histone dimethyltra ...[more]