Ontology highlight
ABSTRACT:
SUBMITTER: Aranda S
PROVIDER: S-EPMC6402848 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Aranda Sergi S Alcaine-Colet Anna A Blanco Enrique E Borràs Eva E Caillot Claire C Sabidó Eduard E Di Croce Luciano L
Science advances 20190306 3
Profiling the chromatin-bound proteome (chromatome) in a simple, direct, and reliable manner might be key to uncovering the role of yet uncharacterized chromatin factors in physiology and disease. Here, we have designed an experimental strategy to survey the chromatome of proliferating cells by using the DNA-mediated chromatin pull-down (Dm-ChP) technology. Our approach provides a global view of cellular chromatome under normal physiological conditions and enables the identification of chromatin ...[more]