Successful debulking of plurihormonal pituitary macroadenoma with long-acting pasireotide and dopamine agonist combination therapy.
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ABSTRACT:
SUBMITTER: Jerkins TW
PROVIDER: S-EPMC6406151 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
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Successful debulking of plurihormonal pituitary macroadenoma with long-acting pasireotide and dopamine agonist combination therapy.
Jerkins Terri W TW Jerkins Randy K RK Franklin Robbi R
Clinical case reports 20190128 3
Long-acting pasireotide and bromocriptine provided biochemical control of growth hormone and prolactin in a patient with plurihormonal pituitary macroadenoma, allowing near-complete tumor excision while restoring pituitary function and avoiding adjunctive radiotherapy. Pasireotide initiation resulted in hyperglycemia, which stabilized after a few months and resolved upon pasireotide discontinuation (ACCESS; NCT01995734). ...[more]
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