Ontology highlight
ABSTRACT:
SUBMITTER: Lin YT
PROVIDER: S-EPMC6406613 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Lin Yi-Ting YT Liang Shu-Man SM Wu Ya-Ju YJ Wu Yi-Ju YJ Lu Yi-Jhu YJ Jan Yee-Jee YJ Ko Bor-Sheng BS Chuang Yung-Jen YJ Shyue Song-Kun SK Kuo Cheng-Chin CC Liou Jun-Yang JY
Cancers 20190201 2
Focal adhesion kinase (FAK) plays an important role in vascular development, including the regulation of endothelial cell (EC) adhesion, migration, proliferation, and survival. 3'-deoxyadenosine (cordycepin) is known to suppress FAK expression, cell migration, and the epithelial⁻mesenchymal transition in hepatocellular carcinoma (HCC). However, whether cordycepin affects FAK expression and cellular functions in ECs and the specific molecular mechanism remain unclear. In this study, we found that ...[more]