Ontology highlight
ABSTRACT:
SUBMITTER: Yoon Y
PROVIDER: S-EPMC6406949 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Yoon Yousang Y Lee Jusin J Ra Moonsoo M Gwon Hyeokshin H Lee Seungwon S Kim Min Young MY Yoo Ki-Chun KC Sul Onejae O Kim Chul Geun CG Kim Whoi-Yul WY Park Jea-Gun JG Lee Su-Jae SJ Lee Young Yiul YY Choi Ho Soon HS Lee Seung-Beck SB
Cancers 20190210 2
The separation of circulating tumor cells (CTCs) from the peripheral blood is an important issue that has been highlighted because of their high clinical potential. However, techniques that depend solely on tumor-specific surface molecules or just the larger size of CTCs are limited by tumor heterogeneity. Here, we present a slanted weir microfluidic device that utilizes the size and deformability of CTCs to separate them from the unprocessed whole blood. By testing its ability using a highly in ...[more]