Dataset Information

Assessment of literacy and numeracy skills related to non-steroidal anti-inflammatory drug labels.

ABSTRACT:

Background

Non-steroidal anti-inflammatory drugs are widely used and have a potential for over-the-counter misuse. Limited health literacy is associated with poor health outcomes. Identification of new strategies to assess literacy and numeracy could be useful in targeting effective education initiatives.

Objective

To characterize numeracy and literacy skills related to non-steroidal anti-inflammatory drug labels in primary care patients.

Methods

Patients were recruited and consented over an 8-month period after their regular primary care visit. Demographic information was collected and two instruments were administered to assess literacy and numeracy skills: (1) a medication label literacy instrument focused on non-steroidal anti-inflammatory drugs (MedLit-NSAID) and (2) a general healthy literacy-screening tool, the Newest Vital Sign. Two questions on the MedLit-NSAID instrument evaluated understanding of the Food and Drug Administration medication guide for non-steroidal anti-inflammatory drugs and the Food and Drug Administration approved over-the-counter label.

Results

A total of 145 patients were enrolled. Mean MedLit-NSAID and Newest Vital Sign scores were 6.8 (scale range 0-8) and 4.2 (scale range 0-6), respectively. Higher education level was associated with higher scores for both tools (p???0.05). Total MedLit-NSAID scores on average were higher in females compared with males (6.5 vs 6, p?=?0.05). Patients with decreased kidney function (n?=?18) had significantly lower MedLit-NSAID scores (p???0.05). Test-retest scores were not significantly different for MedLit-NSAID (p?=?0.32). The correlation between the tools was 0.54 and internal consistency MedLit-NSAID was 0.61.

Conclusion

A medication information focused instrument provided specific information to assess health literacy related to non-steroidal anti-inflammatory drug labels. This information could be utilized to develop patient education initiatives for medication label comprehension.

SUBMITTER: Jang SM

PROVIDER: S-EPMC6407168 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Publications

Assessment of literacy and numeracy skills related to non-steroidal anti-inflammatory drug labels.

Jang Soo Min SM Jiang Ruixin R Grabe Darren D Pai Amy Barton AB

SAGE open medicine 20190307

<h4>Background</h4>Non-steroidal anti-inflammatory drugs are widely used and have a potential for over-the-counter misuse. Limited health literacy is associated with poor health outcomes. Identification of new strategies to assess literacy and numeracy could be useful in targeting effective education initiatives.<h4>Objective</h4>To characterize numeracy and literacy skills related to non-steroidal anti-inflammatory drug labels in primary care patients.<h4>Methods</h4>Patients were recruited and ...[more]

PMID: 30873281

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Project description:Background and objectivesNonsteroidal anti-inflammatory drugs (NSAIDs) have been associated with AKI. Their association with nephrotic syndrome has not been systematically studied. This study aimed to assess the risk of nephrotic syndrome associated with NSAID use.Design, setting, participants, & measurementsA matched case-control study was performed in the UK primary care database. Cases were patients with a first diagnosis of nephrotic syndrome and controls were those without nephrotic syndrome. NSAID exposure (grouped either based on cyclooxygenase enzyme selectivity and chemical groups) was classified as either current (use at the nephrotic syndrome diagnosis date and corresponding date in the control group), recent, or past use. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated using unconditional logistic regression analysis.ResultsWe included 2620 cases and 10,454 controls. Compared with non-use, current use of 15-28 days and >28 days of conventional NSAIDs was associated with a higher relative risk of nephrotic syndrome: adjusted OR, 1.34; 95% CI, 1.06 to 1.70, and OR, 1.42; 95% CI, 0.79 to 2.55, respectively. Also, recent use (discontinuation 1-2 months before nephrotic syndrome diagnosis date; OR, 1.55; 95% CI, 1.11 to 2.15) and past use (discontinuation 2 months-2 years; OR, 1.24; 95% CI, 1.07 to 1.43), but not current use of <15 days (OR, 0.78; 95% CI, 0.46 to 1.31) nor past use (discontinuation >2 years; OR, 0.96; 95% CI, 0.85 to 1.09) were associated with a higher relative risk of nephrotic syndrome as well as past use of selective COX-2 inhibitors (discontinuation 2-24 months; OR, 1.24; 95% CI, 0.98 to 1.58). Categorization based on chemical groups showed that acetic acid and propionic acid derivatives were associated with a higher risk of nephrotic syndrome.ConclusionsThe use of conventional NSAIDs was associated with a higher risk of nephrotic syndrome starting from at least 2 weeks of exposure, as well as for recent and past exposure up to 2 years before the diagnosis of nephrotic syndrome. This higher risk appeared mainly attributable to acetic acid and propionic acid derivatives.

Dataset Information

Assessment of literacy and numeracy skills related to non-steroidal anti-inflammatory drug labels.

Background

Objective

Methods

Results

Conclusion

Publications

Assessment of literacy and numeracy skills related to non-steroidal anti-inflammatory drug labels.

Similar Datasets

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