Ontology highlight
ABSTRACT:
SUBMITTER: Manak MS
PROVIDER: S-EPMC6407716 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Manak Michael S MS Varsanik Jonathan S JS Hogan Brad J BJ Whitfield Matt J MJ Su Wendell R WR Joshi Nikhil N Steinke Nicolai N Min Andrew A Berger Delaney D Saphirstein Robert J RJ Dixit Gauri G Meyyappan Thiagarajan T Chu Hui-May HM Knopf Kevin B KB Albala David M DM Sant Grannum R GR Chander Ashok C AC
Nature biomedical engineering 20180917 10
The risk stratification of prostate cancer and breast cancer tumours from patients relies on histopathology, selective genomic testing, or on other methods employing fixed formalin tissue samples. However, static biomarker measurements from bulk fixed-tissue samples provide limited accuracy and actionability. Here, we report the development of a live-primary-cell phenotypic-biomarker assay with single-cell resolution, and its validation with prostate cancer and breast cancer tissue samples for t ...[more]