The association between body lead levels and childhood rickets: A meta-analysis based on Chinese cohort.

ABSTRACT: China has serious lead pollution and a high incidence of childhood rickets. High lead levels have been reported in childhood rickets, but the results were inconsistent.To evaluate the association between body lead levels and childhood rickets.After a systematic literature search, we identified 15 studies determining body lead levels between rickets children and healthy controls, and 4 studies focusing on the cases of different disease severity. Standard mean differences (SMD) and the corresponding 95% confidence intervals (CI) were pooled to compare the lead levels between different groups.Sixteen case-control studies were included with a total of 5082 cases and 6054 controls. Compared with healthy controls, the body lead levels in rickets children were significantly higher (SMD (95%CI): 0

SUBMITTER: Zhang YF 

PROVIDER: S-EPMC6407931 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature