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Increased risk of neurodegenerative dementia in women with migraines: A nested case-control study using a national sample cohort.


ABSTRACT: The present study aimed to evaluate the association between migraines and dementia.Data were collected from 11,438 dementia participants who were 1:4 matched by age, sex, income, region of residence, hypertension, diabetes, and dyslipidemia with 45,752 controls from the Korean National Health Insurance Service-National Sample Cohort from 2002 to 2013. Dementia was diagnosed using the International Classification of Disease-10 (ICD-10) codes (G30 or F00). For the integrity of diagnoses, we included only participants ?60 years old who had been diagnosed with an ICD-10 code twice or more during ambulatory visits for the same episode. For migraine (ICD-10 code, G43), we included participants who had visited outpatient clinics twice or more for the same episode. In both dementia and control groups, a previous history of migraine was investigated.Approximately 7.7% (881/11,438) of patients in the dementia group and 6.3% (2888/45,752) of those in the control group had a history of migraine (P?

SUBMITTER: Lee SY 

PROVIDER: S-EPMC6408076 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature

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Increased risk of neurodegenerative dementia in women with migraines: A nested case-control study using a national sample cohort.

Lee Sang-Yeon SY   Lim Jae-Sung JS   Oh Dong Jun DJ   Kong Il Gyu IG   Choi Hyo Geun HG  

Medicine 20190201 7


The present study aimed to evaluate the association between migraines and dementia.Data were collected from 11,438 dementia participants who were 1:4 matched by age, sex, income, region of residence, hypertension, diabetes, and dyslipidemia with 45,752 controls from the Korean National Health Insurance Service-National Sample Cohort from 2002 to 2013. Dementia was diagnosed using the International Classification of Disease-10 (ICD-10) codes (G30 or F00). For the integrity of diagnoses, we includ  ...[more]

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