Ontology highlight
ABSTRACT:
SUBMITTER: Gao J
PROVIDER: S-EPMC6410038 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Gao Junfeng J Zhao Mingliang M Duan Xueyan X Wang Yongqiang Y Cao Hong H Li Xiaoqi X Zheng Shijun J SJ
Viruses 20190127 2
Fowl adenovirus serotype 4 (FAdV-4) causes hepatitis-hydropericardium syndrome (HHS), leading to severe economic losses in the poultry industry. Although the pathogenesis of FAdV-4 infection has caused much attention, the underlying molecular mechanisms remain poorly understood. Here, we identified chaperonin containing TCP-1 subunit eta (CCT7) as an interacting partner of the FAdV-4 capsid protein hexon. We found that ectopic expression of CCT7 in leghorn male hepatocellular (LMH) cells enhance ...[more]