Ontology highlight
ABSTRACT:
SUBMITTER: Alhunaidi O
PROVIDER: S-EPMC6411413 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Alhunaidi Omar O Zlotta Alexandre R AR
Ecancermedicalscience 20190226
The high recurrence and progression rates of non-muscle invasive bladder cancer (NMIBC) have led investigators to study the use of intravesical therapy in order to prevent them. Bacillus Calmette-Guérin (BCG) has been successfully used for this indication to treat NMIBC for more than four decades. BCG is the only intravesical agent shown to reduce the risk of progression of NMIBC to muscle-invasive disease. Despite over 40 years of clinical use, the precise mechanism of action for what has often ...[more]