Dataset Information
Metal-Free Alpha Trifluoromethylselenolation of Carbonyl Derivatives under Batch and Flow Conditions.
Ontology highlight
ABSTRACT:
SUBMITTER: Massolo E
PROVIDER: S-EPMC6412565 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Publications
Metal-Free Alpha Trifluoromethylselenolation of Carbonyl Derivatives under Batch and Flow Conditions.
Molecules (Basel, Switzerland) 20190218 4
Trifluoromethylselenolated carbonyl compounds represent an emerging class with potential applications in several fields; however, a widespread use of such compound is hampered by the very limited number of strategies for their preparation. In this study we developed a method for the preparation of α-SeCF₃ substituted carbonyl derivatives using an in situ generated electrophilic ClSeCF₃ species. We also implemented an in-flow protocol to improve the safety features of the process. ...[more]