Ontology highlight
ABSTRACT:
SUBMITTER: Liu Z
PROVIDER: S-EPMC6412568 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Liu Zhangshuan Z Fang Liming L Delaittre Guillaume G Ke Yu Y Wu Gang G
Molecules (Basel, Switzerland) 20190220 4
Traditional methods using coupling chemistry for surface grafting of heparin onto polyurethane (PU) are disadvantageous due to their generally low efficiency. In order to overcome this problem, a quick one-step photografting method is proposed here. Three heparin derivatives incorporating 0.21, 0.58, and 0.88 wt% pendant aryl azide groups were immobilized onto PU surfaces, leading to similar grafting densities of 1.07, 1.17, and 1.13 μg/cm², respectively, yet with increasing densities of anchori ...[more]