Ontology highlight
ABSTRACT:
SUBMITTER: Hallberg P
PROVIDER: S-EPMC6413474 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Hallberg Pär P Smedje Hans H Eriksson Niclas N Kohnke Hugo H Daniilidou Makrina M Öhman Inger I Yue Qun-Ying QY Cavalli Marco M Wadelius Claes C Magnusson Patrik K E PKE Landtblom Anne-Marie AM Wadelius Mia M
EBioMedicine 20190130
<h4>Background</h4>The incidence of narcolepsy rose sharply after the swine influenza A (H1N1) vaccination campaign with Pandemrix. Narcolepsy is an immune-related disorder with excessive daytime sleepiness. The most frequent form is strongly associated with HLA-DQB1*06:02, but only a minority of carriers develop narcolepsy. We aimed to identify genetic markers that predispose to Pandemrix-induced narcolepsy.<h4>Methods</h4>We tested for genome-wide and candidate gene associations in 42 narcolep ...[more]