Ontology highlight
ABSTRACT:
SUBMITTER: Cummings J
PROVIDER: S-EPMC6413822 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Cummings J J Ballard C C Tariot P P Owen R R Foff E E Youakim J J Norton J J Stankovic S S
The journal of prevention of Alzheimer's disease 20180101 4
Psychosis is common across dementia types with a prevalence of 20% to 70%. Currently, no pharmacologic treatment is approved for dementia-related psychosis. Atypical antipsychotics are frequently used to treat these disorders, despite significant safety concerns. Pimavanserin, a selective 5-HT2A inverse agonist/antagonist, was approved in the U.S. for treating hallucinations and delusions associated with Parkinson's disease psychosis (PDP). Patients in the pimavanserin group experienced a signif ...[more]