Ontology highlight
ABSTRACT:
SUBMITTER: Lien HM
PROVIDER: S-EPMC6414523 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Lien Hsiu-Man HM Wu Hui-Yu HY Hung Chiu-Lien CL Chen Chih-Jung CJ Wu Chia-Lin CL Chen Kuan-Wen KW Huang Chao-Lu CL Chang Sheau-Jiun SJ Chen Chia-Chang CC Lin Hwai-Jeng HJ Lai Chih-Ho CH
Scientific reports 20190312 1
Helicobacter pylori infection is associated with high incidence of gastric diseases. The extensive therapy of H. pylori infection with antibiotics has increased its resistance rates worldwide. Ovatodiolide, a pure constituent isolated from Anisomeles indica, has been demonstrated to possess bactericidal activity against H. pylori. In this study, ovatodiolide inhibited the growth of both H. pylori reference strain and clinical multidrug-resistant isolates. Docking analysis revealed that ovatodiol ...[more]