Dataset Information

Macro-scale ore-controlling faults revealed by micro-geochemical anomalies.

ABSTRACT: Whereas the mechanism of fluid flow, and thus structural control, linked with mineral deposit formation is quite understood, the specific structures that likely provided controls on mineralization at certain geographic scales are not readily known for a given region unless it is well-explored. This contributes uncertainty in mineral prospectivity analysis in poorly-explored regions (or greenfields). Here, because the spatial distribution of mineral deposits has been postulated to be fractals (i.e., the patterns of these features are self-similar across a range of spatial scales), we show for the first time that micro-geochemical anomalies (as proxies of micro-scale patterns of ore minerals), from few discrete parts of the Sossego iron-oxide copper-gold (IOCG) deposit in the Carajás Mineral Province (CMP) of Brazil, exhibit trends of macro-scale faults that are known to have controlled IOCG mineralization in the CMP. The methodology described here, which led to this novel finding, would help towards detecting mineral exploration targets as well as help towards understanding structural controls on mineralization in greenfields.

SUBMITTER: Carranza EJM

PROVIDER: S-EPMC6416276 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

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Macro-scale ore-controlling faults revealed by micro-geochemical anomalies.

Carranza Emmanuel John M EJM de Souza Filho Carlos Roberto CR Haddad-Martim Paulo Miguel PM Katsuta Nagayoshi N Shimizu Ichiko I

Scientific reports 20190313 1

Whereas the mechanism of fluid flow, and thus structural control, linked with mineral deposit formation is quite understood, the specific structures that likely provided controls on mineralization at certain geographic scales are not readily known for a given region unless it is well-explored. This contributes uncertainty in mineral prospectivity analysis in poorly-explored regions (or greenfields). Here, because the spatial distribution of mineral deposits has been postulated to be fractals (i. ...[more]

PMID: 30867539

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Project description:The striatum comprises of multiple functional territories involved with multilevel control of behavior. Disinhibition of different functional territories leads to territory-specific hyperkinetic and hyperbehavioral symptoms. The ventromedial striatum, including the nucleus accumbens (NAc) core, is typically associated with limbic input but was historically linked to high-level motor control. In this study, performed in female Long-Evans rats, we show that the NAc core directly controls motor behavior on multiple timescales. On the macro-scale, following NAc disinhibition, the animals manifested prolonged hyperactivity, expressed as excessive normal behavior, whereas on the micro-scale multiple behavior transitions occurred, generating short movement segments. The underlying striatal network displayed population-based local field potential transient deflections (LFP spikes) whose rate determined the magnitude of the hyperactivity and whose timing corresponded to unitary behavioral transition events. Individual striatal neurons preserved normal baseline activity and network interactions following the disinhibition, maintaining the normal encoding of behavioral primitives and forming a sparse link between the LFP spikes and single neuron activity. Disinhibition of this classically limbic territory leads to profound motor changes resembling hyperactivity and attention deficit. These behavioral and neuronal results highlight the direct interplay on multiple timescales between different striatal territories during normal and pathological conditions.SIGNIFICANCE STATEMENT The nucleus accumbens (NAc) is a key part of the striatal limbic territory. In the current study we show that this classically limbic area directly controls motor behavior on multiple timescales. Focal disinhibition of the NAc core in freely behaving rats led to macro-scale hyperactivity and micro-scale behavioral transitions, symptoms typically associated with attention deficit hyperactivity disorder. The behavioral changes were encoded by the striatal LFP signal and single-unit spiking activity in line with the neuronal changes observed during tic expression following disinhibition of the striatal motor territory. These results point to the need to extend the existing parallel functional pathway concept of basal ganglia function to include the study of limbic-motor cross-territory interactions in both health and disease.

Dataset Information

Macro-scale ore-controlling faults revealed by micro-geochemical anomalies.

Publications

Macro-scale ore-controlling faults revealed by micro-geochemical anomalies.

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