Repeated administration of the NSAID meloxicam alters the plasma and urine lipidome.
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ABSTRACT:
SUBMITTER: Rivera-Velez SM
PROVIDER: S-EPMC6416286 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Publications
Repeated administration of the NSAID meloxicam alters the plasma and urine lipidome.
Rivera-Velez Sol M SM Broughton-Neiswanger Liam E LE Suarez Martin M Piñeyro Pablo P Navas Jinna J Chen Sandy S Hwang Julianne J Villarino Nicolas F NF
Scientific reports 20190313 1
Non-steroidal anti-inflammatories (NSAIDs), such as meloxicam, are the mainstay for treating painful and inflammatory conditions in animals and humans; however, the repeated administration of NSAIDs can cause adverse effects, limiting the long-term administration of these drugs to some patients. The primary aim of this study was to determine the effects of repeated meloxicam administration on the feline plasma and urine lipidome. Cats (n = 12) were treated subcutaneously with either saline solut ...[more]
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