Ontology highlight
ABSTRACT:
SUBMITTER: Shey RA
PROVIDER: S-EPMC6416346 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Shey Robert Adamu RA Ghogomu Stephen Mbigha SM Esoh Kevin Kum KK Nebangwa Neba Derrick ND Shintouo Cabirou Mounchili CM Nongley Nkemngo Francis NF Asa Bertha Fru BF Ngale Ferdinand Njume FN Vanhamme Luc L Souopgui Jacob J
Scientific reports 20190313 1
Onchocerciasis is a parasitic disease with high socio-economic burden particularly in sub-Saharan Africa. The elimination plan for this disease has faced numerous challenges. A multi-epitope prophylactic/therapeutic vaccine targeting the infective L3 and microfilaria stages of the parasite's life cycle would be invaluable to achieve the current elimination goal. There are several observations that make the possibility of developing a vaccine against this disease likely. For example, despite bein ...[more]