Ontology highlight
ABSTRACT:
SUBMITTER: Casale AM
PROVIDER: S-EPMC6416348 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Scientific reports 20190313 1
A very important open question in stem cells regulation is how the fine balance between GSCs self-renewal and differentiation is orchestrated at the molecular level. In the past several years much progress has been made in understanding the molecular mechanisms underlying intrinsic and extrinsic controls of GSC regulation but the complex gene regulatory networks that regulate stem cell behavior are only partially understood. HP1 is a dynamic epigenetic determinant mainly involved in heterochroma ...[more]