Ontology highlight
ABSTRACT:
SUBMITTER: Li X
PROVIDER: S-EPMC6417431 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Methods in molecular biology (Clifton, N.J.) 20170101
For over a decade, genome-wide association studies (GWAS) have been a major tool for detecting genetic variants underlying complex traits. Recent studies have demonstrated that the same variant or gene can be associated with multiple traits, and such associations are termed cross-phenotype (CP) associations. CP association analysis can improve statistical power by searching for variants that contribute to multiple traits, which is often relevant to pleiotropy. In this chapter, we discuss existin ...[more]