Towards homochiral supramolecular entities from achiral molecules by vortex mixing-accompanied self-assembly.

ABSTRACT: Achieving homochirality is challenging both at the molecular and the supramolecular levels. While the origin of molecular homochirality still remains mysterious, the fabrication of homochiral assemblies from achiral molecules has attracted considerable interest since it provides many clues to understand the origin of molecular chirality. Here, by using a vortex mixing-accompanied self-assembly strategy, we obtained near-unity homochiral entities with controlled handedness from supramolecular gels that consist of exclusively achiral molecules without any chiral additives. The common supramolecular gelation process via heating and cooling of the achiral molecules only resulted in racemic gels. However, if vortex mixing is applied during the self-assembly, near-unity homochiral assembl

SUBMITTER: Sang Y 

PROVIDER: S-EPMC6419933 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature