Fighting Staphylococcus aureus Biofilms with Monoclonal Antibodies.
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ABSTRACT:
SUBMITTER: Raafat D
PROVIDER: S-EPMC6420399 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Publications
Fighting Staphylococcus aureus Biofilms with Monoclonal Antibodies.
Raafat Dina D Otto Michael M Reppschläger Kevin K Iqbal Jawad J Holtfreter Silva S
Trends in microbiology 20190119 4
Staphylococcus aureus (S. aureus) is a notorious pathogen and one of the most frequent causes of biofilm-related infections. The treatment of S. aureus biofilms is hampered by the ability of the biofilm structure to shield bacteria from antibiotics as well as the host's immune system. Therefore, new preventive and/or therapeutic interventions, including the use of antibody-based approaches, are urgently required. In this review, we describe the mechanisms by which anti-S. aureus antibodies can h ...[more]
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