Capillary leak-syndrome triggered by Maripa virus in French Guiana: case report and implication for pathogenesis.

ABSTRACT:

Background

We report hereby a severe case of Hantavirus Pulmonary Syndrome" (HPS) induced by Maripa virus in French Guiana and describe the mechanism of severity of the human disease.

Case presentation

A 47-year- old patient started presenting a prodromic period with fever, dyspnea, cough and head ache. This clinical presentation was followed by a rapid respiratory, hemodynamic and renal failure leading to admission in the ICU. Biological exams revealed an increased haematocrit level with a paradoxical low protein level. Echocardiographic and hemodynamic monitoring showed a normal left ventricular function with low filling pressures, an elevated extravascular lung water index and pulmonary vascular permeability index. These findings were compatible with a capillary leak-synd

SUBMITTER: Kallel H 

PROVIDER: S-EPMC6420753 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature