Ontology highlight
ABSTRACT:
SUBMITTER: Crowley NA
PROVIDER: S-EPMC6420859 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Crowley Nicole A NA Magee Sarah N SN Feng Mengyang M Jefferson Sarah J SJ Morris Christian J CJ Dao Nigel C NC Brockway Dakota F DF Luscher Bernhard B
Neuropharmacology 20190204
Ketamine is a fast acting experimental antidepressant with significant therapeutic potential for emotional disorders such as major depressive disorder and alcohol use disorders. Of particular interest is binge alcohol use, which during intermittent withdrawal from drinking involves depressive-like symptoms reminiscent of major depressive disorder. Binge drinking has been successfully modeled in mice with the Drinking in the Dark (DID) paradigm, which involves daily access to 20% ethanol, for a l ...[more]