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Associations between ADIPOQ polymorphisms and coronary artery disease: a meta-analysis.


ABSTRACT: BACKGROUND:Whether adiponectin (ADIPOQ) polymorphisms are associated with coronary artery disease (CAD) remain controversial. Therefore, we performed this meta-analysis to better explore potential roles of ADIPOQ polymorphisms in CAD. METHODS:PubMed, Web of Science, Embase and CNKI were searched for eligible studies. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated. RESULTS:Totally 45 studies were included for pooled analyses. A significant association with the susceptibility to CAD was detected for rs2241766 (dominant model: p?=?0.0009, OR?=?0.82, 95%CI 0.73-0.92; recessive model: p?=?0.04, OR?=?1.29, 95%CI 1.02-1.64; allele model: p?

SUBMITTER: Zhang X 

PROVIDER: S-EPMC6421689 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

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Associations between ADIPOQ polymorphisms and coronary artery disease: a meta-analysis.

Zhang Xia X   Cao Yan Jun YJ   Zhang Hong Yu HY   Cong Hongliang H   Zhang Jian J  

BMC cardiovascular disorders 20190318 1


<h4>Background</h4>Whether adiponectin (ADIPOQ) polymorphisms are associated with coronary artery disease (CAD) remain controversial. Therefore, we performed this meta-analysis to better explore potential roles of ADIPOQ polymorphisms in CAD.<h4>Methods</h4>PubMed, Web of Science, Embase and CNKI were searched for eligible studies. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated.<h4>Results</h4>Totally 45 studies were included for pooled analyses. A significant association w  ...[more]

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