Dataset Information

IARNN-Based Semantic-Containing Double-Level Embedding Bi-LSTM for Question-and-Answer Matching.

ABSTRACT: We propose a novel end-to-end approach, namely, the semantic-containing double-level embedding Bi-LSTM model (SCDE-Bi-LSTM), to solve the three key problems of Q&A matching in the Chinese medical field. In the similarity calculation of the Q&A core module, we propose a text similarity calculation method that contains semantic information, to solve the problem that previous Q&A methods do not incorporate the deep information of a sentence into the similarity calculations. For the sentence vector representation module, we present a double-level embedding sentence representation method to reduce the error caused by Chinese medical word segmentation. In addition, due to the problem of the attention mechanism tending to cause backward deviation of the features, we propose an improved algorithm based on Bi-LSTM in the feature extraction stage. The Q&A framework proposed in this paper not only retains important timing features but also loses low-frequency features and noise. Additionally, it is applicable to different domains. To verify the framework, extensive Chinese medical Q&A corpora are created. We run several state-of-the-art Q&A methods as contrastive experiments on the medical corpora and the current popular insuranceQA dataset under different performance measures. The experimental results on the medical corpora show that our framework significantly outperforms several strong baselines and achieves an improvement of top-1 accuracy of up to 14%, reaching 79.15%.

SUBMITTER: Xiong CZ

PROVIDER: S-EPMC6421739 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Publications

IARNN-Based Semantic-Containing Double-Level Embedding Bi-LSTM for Question-and-Answer Matching.

Xiong Chang-Zhu CZ Su Minglian M

Computational intelligence and neuroscience 20190303

We propose a novel end-to-end approach, namely, the semantic-containing double-level embedding Bi-LSTM model (SCDE-Bi-LSTM), to solve the three key problems of Q&A matching in the Chinese medical field. In the similarity calculation of the Q&A core module, we propose a text similarity calculation method that contains semantic information, to solve the problem that previous Q&A methods do not incorporate the deep information of a sentence into the similarity calculations. For the sentence vector ...[more]

PMID: 30944556

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Project description:BackgroundWith the increasing variety of drugs, the incidence of adverse drug events (ADEs) is increasing year by year. Massive numbers of ADEs are recorded in electronic medical records and adverse drug reaction (ADR) reports, which are important sources of potential ADR information. Meanwhile, it is essential to make latent ADR information automatically available for better postmarketing drug safety reevaluation and pharmacovigilance.ObjectiveThis study describes how to identify ADR-related information from Chinese ADE reports.MethodsOur study established an efficient automated tool, named BBC-Radical. BBC-Radical is a model that consists of 3 components: Bidirectional Encoder Representations from Transformers (BERT), bidirectional long short-term memory (bi-LSTM), and conditional random field (CRF). The model identifies ADR-related information from Chinese ADR reports. Token features and radical features of Chinese characters were used to represent the common meaning of a group of words. BERT and Bi-LSTM-CRF were novel models that combined these features to conduct named entity recognition (NER) tasks in the free-text section of 24,890 ADR reports from the Jiangsu Province Adverse Drug Reaction Monitoring Center from 2010 to 2016. Moreover, the man-machine comparison experiment on the ADE records from Drum Tower Hospital was designed to compare the NER performance between the BBC-Radical model and a manual method.ResultsThe NER model achieved relatively high performance, with a precision of 96.4%, recall of 96.0%, and F1 score of 96.2%. This indicates that the performance of the BBC-Radical model (precision 87.2%, recall 85.7%, and F1 score 86.4%) is much better than that of the manual method (precision 86.1%, recall 73.8%, and F1 score 79.5%) in the recognition task of each kind of entity.ConclusionsThe proposed model was competitive in extracting ADR-related information from ADE reports, and the results suggest that the application of our method to extract ADR-related information is of great significance in improving the quality of ADR reports and postmarketing drug safety evaluation.

Project description:The proliferation of the scientific literature in the field of biomedicine makes it difficult to keep abreast of current knowledge, even for domain experts. While general Web search engines and specialized information retrieval (IR) systems have made important strides in recent decades, the problem of accurate knowledge extraction from the biomedical literature is far from solved. Classical IR systems usually return a list of documents that have to be read by the user to extract relevant information. This tedious and time-consuming work can be lessened with automatic Question Answering (QA) systems, which aim to provide users with direct and precise answers to their questions. In this work we propose a novel methodology for QA based on semantic relations extracted from the biomedical literature.We extracted semantic relations with the SemRep natural language processing system from 122,421,765 sentences, which came from 21,014,382 MEDLINE citations (i.e., the complete MEDLINE distribution up to the end of 2012). A total of 58,879,300 semantic relation instances were extracted and organized in a relational database. The QA process is implemented as a search in this database, which is accessed through a Web-based application, called SemBT (available at http://sembt.mf.uni-lj.si ). We conducted an extensive evaluation of the proposed methodology in order to estimate the accuracy of extracting a particular semantic relation from a particular sentence. Evaluation was performed by 80 domain experts. In total 7,510 semantic relation instances belonging to 2,675 distinct relations were evaluated 12,083 times. The instances were evaluated as correct 8,228 times (68%).In this work we propose an innovative methodology for biomedical QA. The system is implemented as a Web-based application that is able to provide precise answers to a wide range of questions. A typical question is answered within a few seconds. The tool has some extensions that make it especially useful for interpretation of DNA microarray results.

Dataset Information

IARNN-Based Semantic-Containing Double-Level Embedding Bi-LSTM for Question-and-Answer Matching.

Publications

IARNN-Based Semantic-Containing Double-Level Embedding Bi-LSTM for Question-and-Answer Matching.

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