Ontology highlight
ABSTRACT:
SUBMITTER: Sakurai S
PROVIDER: S-EPMC6423288 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Sakurai Sho S Inai Yoko Y Minakata Shiho S Manabe Shino S Ito Yukishige Y Ihara Yoshito Y
Scientific reports 20190318 1
C-Mannosyl tryptophan (C-Man-Trp) is a unique molecule in that an α-mannose is connected to the indole C2 carbon atom of a Trp residue via C-glycosidic linkage. Although serum C-Man-Trp may be a novel biomarker of renal function in humans, the biological significance of C-Man-Trp has yet to be fully investigated. In this study, a novel assay system for C-Man-Trp was established using hydrophilic-interaction liquid chromatography, followed by detecting the fluorescence intensity or mass abundance ...[more]