Case-Control Study of Cryptosporidium Transmission in Bangladeshi Households.

ABSTRACT:

Background

Cryptosporidium is a leading contributor to diarrheal morbidity and mortality in under-5 children worldwide. As there is no vaccine and no effective drug therapy in young children for this infection, preventing infection is critical. We undertook a pilot case-control study to define the extent of person-to-person transmission of cryptosporidiosis within an urban and a rural community in Bangladesh.

Methods

We enrolled 48 case families with a Cryptosporidium-infected child aged 6-18 months. Controls were age- and sex-matched Cryptosporidium-negative children in 12 households. Children and household members were followed for 8 weeks with weekly illness survey and stool testing with quantitative polymerase chain reaction for Cryptosporidium.

Results

In the 24

SUBMITTER: Korpe PS 

PROVIDER: S-EPMC6424084 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature