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Multiple abscesses in the lower extremities caused by Trichophyton rubrum.


ABSTRACT: BACKGROUND:Dermatophytes are keratinophilic fungi, that usually infect the hair, stratum corneum, and nails. However, dermatophytes occasionally invade the dermis, subcutaneous tissues, and internal organs, resulting in a condition called deep dermatophytosis. We report a case of an unusual presentation of Trichophyton rubrum infection causing multiple fungal abscesses in the lower extremities of an immunocompromised patient. CASE PRESENTATION:A 66-year-old male who had been receiving immunosuppressive drugs for 7?years developed numerous subcutaneous nodules in the lower extremities. The yellow purulent fluid obtained from the cyst was positive for T. rubrum. Topical bifonazole cream was effective for tinea pedis, but oral Sporanox 400?mg/day was discontinued after 2?months because the patient died from pneumonia after hospitalization for a lumbar fracture. CONCLUSIONS:Although deep dermatophytosis is very rare, dermatomycosis should be considered in any examination of patients who are receiving immunosuppressive drugs. Fungi can enter the bloodstream and disseminate to distant major organs, including the lymph nodes, liver, brain, and bone, which often causes systemic infections that can be fatal.

SUBMITTER: Dai Y 

PROVIDER: S-EPMC6425592 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

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Multiple abscesses in the lower extremities caused by Trichophyton rubrum.

Dai Yeqin Y   Xia Xiujiao X   Shen Hong H  

BMC infectious diseases 20190320 1


<h4>Background</h4>Dermatophytes are keratinophilic fungi, that usually infect the hair, stratum corneum, and nails. However, dermatophytes occasionally invade the dermis, subcutaneous tissues, and internal organs, resulting in a condition called deep dermatophytosis. We report a case of an unusual presentation of Trichophyton rubrum infection causing multiple fungal abscesses in the lower extremities of an immunocompromised patient.<h4>Case presentation</h4>A 66-year-old male who had been recei  ...[more]

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