Native coronary artery thrombosis in the setting of heparin-induced thrombocytopenia: a case report.

ABSTRACT:

Background

Heparin-induced thrombocytopenia (HIT) is a rare complication of heparin therapy. Its pathogenesis includes thrombotic events that can rarely affect the coronary arteries.

Case summary

We report a 67-year-old woman who presented with extensive lower extremities deep venous thrombosis. After being treated with heparin, she developed an ST-elevation myocardial infarction secondary to an acute thrombus formation. The patient's platelets dropped within 6 days from the procedure and her heparin-PF4 IgG antibody and serotonin release assay were positive confirming the diagnosis of HIT.

Discussion

Prothrombotic states, such as HIT, are associated with increased risk for coronary thrombosis and ischaemia. Heparin-induced thrombocytopenia can cause coronary complica

SUBMITTER: Almeqdadi M 

PROVIDER: S-EPMC6426051 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature