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Adverse side effects of dexamethasone in surgical patients.


ABSTRACT:

SUBMITTER: Polderman JA 

PROVIDER: S-EPMC6426282 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature

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Adverse side effects of dexamethasone in surgical patients.

Polderman Jorinde Aw JA   Farhang-Razi Violet V   Van Dieren Susan S   Kranke Peter P   DeVries J Hans JH   Hollmann Markus W MW   Preckel Benedikt B   Hermanides Jeroen J  

The Cochrane database of systematic reviews 20181123


<h4>Background</h4>In the perioperative period, dexamethasone is widely and effectively used for prophylaxis of postoperative nausea and vomiting (PONV), for pain management, and to facilitate early discharge after ambulatory surgery.Long-term treatment with steroids has many side effects, such as adrenal insufficiency, increased infection risk, hyperglycaemia, high blood pressure, osteoporosis, and development of diabetes mellitus. However, whether a single steroid load during surgery has negat  ...[more]

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