Ontology highlight
ABSTRACT:
SUBMITTER: Chaker-Margot M
PROVIDER: S-EPMC6426289 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
RNA (New York, N.Y.) 20190122 4
The eukaryotic ribosome is assembled through a complex process involving more than 200 factors. As preribosomal RNA is transcribed, assembly factors bind the nascent pre-rRNA and guide its correct folding, modification, and cleavage. While these early events in the assembly of the small ribosomal subunit have been relatively well characterized, assembly of the large subunit precursors, or pre-60S, is less well understood. Recent structures of nucleolar intermediates of large subunit assembly hav ...[more]