The association between vascular endothelial growth factor gene polymorphisms and stroke: A PRISMA-compliant meta-analysis.

ABSTRACT:

Background

Numerous studies showed that vascular endothelial growth factor (VEGF) gene polymorphisms were linked with the regularity of stroke, but the results remained controversial. The aim of this meta-analysis was to determine the associations between VEGF gene polymorphisms and the risk of stroke.

Methods

A systematic literature search of PubMed, Embase, Wed of Science, The Cochrane Library, Elsevier, China National Knowledge Infrastructure, China Biology Medicine disc, WanFang Data, VIP Database for Chinese Technical Periodicals, and Science paper Online was conducted. Two authors independently assessed trial quality and extracted data. The pooled odds ratio (OR) with 95% confidence interval (CI) was used to assess the strength of associations. Begger funnel plot and E

SUBMITTER: Xu B 

PROVIDER: S-EPMC6426541 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature