Ontology highlight
ABSTRACT:
SUBMITTER: Spetz J
PROVIDER: S-EPMC6426909 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Spetz Johan J Langen Britta B Rudqvist Nils-Petter NP Parris Toshima Z TZ Shubbar Emman E Dalmo Johanna J Wängberg Bo B Nilsson Ola O Helou Khalil K Forssell-Aronsson Eva E
EJNMMI research 20190320 1
<h4>Background</h4><sup>177</sup>Lu-octreotate is used for therapy of somatostatin receptor expressing neuroendocrine tumors with promising results, although complete tumor remission is rarely seen. Previous studies on nude mice bearing the human small intestine neuroendocrine tumor, GOT1, have shown that a priming injection of <sup>177</sup>Lu-octreotate 24 h before the main injection of <sup>177</sup>Lu-octreotate resulted in higher <sup>177</sup>Lu concentration in tumor, resulting in increas ...[more]