Ontology highlight
ABSTRACT:
SUBMITTER: Ni G
PROVIDER: S-EPMC6428271 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Ni Guoying G Chen Shu S Yuan Jianwei J Cavezza Shelley F SF Wei Ming Q MQ Li Hejie H Pan Xuan X Liu Xiaosong X Wang Tianfang T
PloS one 20190321 3
Blocking cytokine interleukin 10 (IL-10) at the time of immunisation enhances vaccine induced T cell responses and improves control of tumour cell growth in vivo. However, the effect of an IL-10 blockade on the biological function of macrophages has not been explored. In the current paper, a macrophage precursor cell line, U937 cells, was selected to investigate the differential expression of proteins and relevant cell signalling pathway changes, when stimulated with lipopolysaccharide (LPS) in ...[more]